CLEVIPREX video resource library

The pharmacology of CLEVIPREX¹

CLEVIPREX is titrated to the desired reduction in BP. The effect of CLEVIPREX appears to plateau at approximately 25% of baseline systolic pressure. The infusion rate for which half the maximal effect is observed is approximately 10 mg/h.

Mechanism of action¹

CLEVIPREX works by selectively dilating arterial smooth muscle via calcium channel blockade, reducing systemic vascular resistance without affecting preload.

Dosing and Administration¹

CLEVIPREX offers non–weight-based dosing and is not dependent on hepatic or renal function. The ready-to-use vials are available in 50 and 100 mL for individualized, titratable administration.