Ordering Information for CLEVIPREX® (clevidipine)
CLEVIPREX® (1 box of 10, 50 mL vials)
CLEVIPREX® (1 box of 10, 100 mL vials)
CLEVIPREX® is a wholesaler-stocked product. Please use standard ordering procedure through your wholesaler. If product is not available at your wholesaler, your wholesaler can easily coordinate a drop shipment via Next-Day Saver from a Chiesi USA distribution provider.
Wholesaler item numbers for liquid vials
|Wholesaler||25 mg/50 mL||50 mg/100 mL|
|Morris & Dickson||239160||239210|
For questions not answered on this website, contact Chiesi USA, Inc. Medical Information at 1-888-661-9260.
CLEVIPREX® is supplied as a sterile, milky-white lipid emulsion in single-use 50 mL and 100 mL glass vials at a concentration of 0.5 mg/mL of clevidipine for intravenous administration.1
CLEVIPREX® is rapidly metabolized by blood and tissue esterases; initial phase half life of approximately 1 minute.1
Mechanism of action
CLEVIPREX® blocks the entry of calcium through L-type calcium channels which mediate the influx of calcium during depolarization in arterial smooth muscle, decreasing systemic vascular resistance and resulting in a reduction of mean arterial pressure.1
Leave vials in cartons until use. Clevidipine is photosensitive and storage in cartons protects against photodegradation. Protection from light during administration is not required.1
Store vials refrigerated at 2°C–8°C (36°F–46°F). Do not freeze. Vials in cartons may be transferred to 25°C (77°F, USP controlled room temperature) for a period not to exceed 2 months. Upon transfer to room temperature, mark vials in cartons: "This product was removed from the refrigerator on _/_/_ date. It must be used or discarded 2 months after this date or the labeled expiration date (whichever date comes first)." Do not return to refrigerated storage after beginning room temperature storage.1
Reference: 1. CLEVIPREX® (clevidipine) Prescribing Information. 2013.